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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 243847Generated: October 25, 2026

Tert-butyl octahydropyrrolo(3,4-c)pyrrole-2-carboxylate → 2-(4,6-Dimethoxy-pyrimidin-2-yl)-octahydro-pyrrolo[3,4-c]pyrrole

https://huagongshe.com/reaction/243847

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-butyl octahydropyrrolo(3,4-c)pyrrole-2-carboxylateHCID 4142526—
Reactant2-Chloro-4,6-dimethoxypyrimidineHCID 5152323—
Product2-(4,6-Dimethoxy-pyrimidin-2-yl)-octahydro-pyrrolo[3,4-c]pyrroleHCID 67116491—

Reaction Steps

The title compound was prepared in a manner analogous to Intermediate 23 utilizing 2-chloro-4,6-dimethoxypyrimidine and hexahydro-pyrrolo[3,4-c]pyrrole-2-carboxylic acid tert-butyl ester as starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08653263B2
Source datasetuspto-grants-2014_02
ORD IDord-72a202a5017648db8fbf1a008883f11c
Source noteuspto-grants-2014_02