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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 24388Generated: October 25, 2026

5-Isopropyl-4-methoxy-2-methylbenzaldehyde → 5-Fluoro-3-(5-isopropyl-4-methoxy-2-methylbenzylidene)-1,3-dihydroindol-2-one

https://huagongshe.com/reaction/24388

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Isopropyl-4-methoxy-2-methylbenzaldehydeHCID 3276129—
Reactant5-fluoro-1,3-dihydro-2H-indol-2-oneHCID 3731012—
Product5-Fluoro-3-(5-isopropyl-4-methoxy-2-methylbenzylidene)-1,3-dihydroindol-2-oneHCID 53974949—

Reaction Steps

5-Isopropyl-4-methoxy-2-methylbenzaldehyde was condensed with 5-fluoro-2-oxindole to give 0.25 g of 5-fluoro-3-(5-isopropyl-4-methoxy-2-methylbenzylidene)-1,3-dihydroindol-2-one as a yellow-orange solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06855730B2
Source datasetuspto-grants-2005_02
ORD IDord-171b7182483449f2a33cef67525df034
Source noteuspto-grants-2005_02