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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 243907Generated: October 25, 2026

2-(Thiophen-2-yl)benzoic acid → 2-{5-[(2-Thiophen-2-ylphenyl)carbonyl]hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}quinoxaline

https://huagongshe.com/reaction/243907

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Thiophen-2-yl)benzoic acidHCID 5105623—
Reactant2-(Hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-quinoxalineHCID 61037281—
Product2-{5-[(2-Thiophen-2-ylphenyl)carbonyl]hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}quinoxalineHCID 52916846—

Reaction Steps

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 35 and 2-thiophen-2-yl-benzoic acid. MS (ESI) mass calcd. for C25H22N4OS, 426.54; m/z found, 427.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08653263B2
Source datasetuspto-grants-2014_02
ORD IDord-94b810ae07f74e91a6eb9c17cdad23df
Source noteuspto-grants-2014_02