Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 243916Generated: October 25, 2026

2-(4-Fluorophenyl)benzoic acid → 2-{5-[(4'-Fluorobiphenyl-2-yl)carbonyl]hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}quinoxaline

https://huagongshe.com/reaction/243916

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Fluorophenyl)benzoic acidHCID 2782687—
Reactant2-(Hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-quinoxalineHCID 61037281—
Product2-{5-[(4'-Fluorobiphenyl-2-yl)carbonyl]hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}quinoxalineHCID 52916933—

Reaction Steps

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 35 and 4′-fluoro-biphenyl-2-carboxylic acid. MS (ESI) mass calcd. for C27H23FN4O, 438.51; m/z found, 439.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08653263B2
Source datasetuspto-grants-2014_02
ORD IDord-8ea1d7758f264052947b13ee3b075cd5
Source noteuspto-grants-2014_02