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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 24392Generated: October 25, 2026

5-Bromo-2-oxindole → 5-Bromo-3-(2,2-dimethylchroman-6-ylmethylene)-1,3-dihydroindol-2-one

https://huagongshe.com/reaction/24392

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-2-oxindoleHCID 611193—
Reactant2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-6-carbaldehydeHCID 1797751—
Product5-Bromo-3-(2,2-dimethylchroman-6-ylmethylene)-1,3-dihydroindol-2-oneHCID 54000435—

Reaction Steps

2,2-Dimethyl-6-formylchromane (commercially available) was condensed with 5-bromo-2-oxindole to give 0.3 g of 5-bromo-3-(2,2-dimethylchroman-6-ylmethylene)-1,3-dihydroindol-2-one as a yellow-orange solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06855730B2
Source datasetuspto-grants-2005_02
ORD IDord-d39590ce9d274943b382813886158a39
Source noteuspto-grants-2005_02