HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4-(thiophen-2-yl)pyrimidine → 2-(Biphenyl-2-ylcarbonyl)-5-(4-thiophen-2-ylpyrimidin-2-yl)octahydropyrrolo[3,4-c]pyrrole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4-(thiophen-2-yl)pyrimidine | HCID 14117941 | — |
| Reactant | Biphenyl-2-yl-(hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-methanone | HCID 67116416 | — |
| Product | 2-(Biphenyl-2-ylcarbonyl)-5-(4-thiophen-2-ylpyrimidin-2-yl)octahydropyrrolo[3,4-c]pyrrole | HCID 52917089 | — |
Reaction Steps
The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 17 and 2-chloro-4-thiophen-2-yl-pyrimidine. MS (ESI) mass calcd. for C27H24N4OS, 452.57; m/z found, 453.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08653263B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-f07b497c145d4ab38659ef90b62212c6 |
| Source note | uspto-grants-2014_02 |