Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 243930Generated: October 27, 2026

2-Chloro-4,6-dimethylpyrimidine → 2-(Biphenyl-2-ylcarbonyl)-5-(4,6-dimethylpyrimidin-2-yl)octahydropyrrolo[3,4-c]pyrrole

https://huagongshe.com/reaction/243930

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-4,6-dimethylpyrimidineHCID 20550—
ReactantBiphenyl-2-yl-(hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-methanoneHCID 67116416—
Product2-(Biphenyl-2-ylcarbonyl)-5-(4,6-dimethylpyrimidin-2-yl)octahydropyrrolo[3,4-c]pyrroleHCID 67116901—

Reaction Steps

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 17 and 2-chloro-4,6-dimethyl-pyrimidine. MS (ESI) mass calcd. for C25H26N4O, 398.5; m/z found, 399.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08653263B2
Source datasetuspto-grants-2014_02
ORD IDord-3e00290fd48a492681796455ef04e7db
Source noteuspto-grants-2014_02