3-Chloro-2,5-dimethylpyrazine → HCID 52917321, compound

HRID 243935Notes

Reaction equation

HRID 243935 reaction equation
[CH2:1]1[CH:5]2[CH2:6][NH:7][CH2:8][CH:4]2[CH2:3][N:2]1[C:9]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[C:17]1[S:18][CH:19]=[CH:20][CH:21]=1)=[O:10].Cl[C:23]1[C:24]([CH3:30])=[N:25][CH:26]=[C:27]([CH3:29])[N:28]=1>>[CH3:29][C:27]1[C:26]([N:7]2[CH2:8][CH:4]3[CH:5]([CH2:1][N:2]([C:9]([C:11]4[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=4[C:17]4[S:18][CH:19]=[CH:20][CH:21]=4)=[O:10])[CH2:3]3)[CH2:6]2)=[N:25][C:24]([CH3:30])=[CH:23][N:28]=1

Participants

3

Reactant 2

HCID 667713-Chloro-2,5-dimethylpyrazineHCID 67116155(Hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-(2-thiophen-2-yl-phenyl)-methanone

Product 1

HCID 52917321HCID 52917321, compound

Procedure

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 37 and 3-chloro-2,5-dimethyl-pyrazine. MS (ESI) mass calcd. for C23H24N4OS, 404.54; m/z found, 405.2 [M+H]+.

Sources & evidence

ORD record
ord-fb08f7baed58406cbf55930d61b1243e
Source dataset
uspto-grants-2014_02
Patent number
US08653263B2

Reaction notes

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