2-Chloro-3,5-dimethylpyrazine → HCID 52917387, compound

HRID 243936Notes

Reaction equation

HRID 243936 reaction equation
[C:1]1([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]([N:9]1[CH2:16][CH:15]2[CH:11]([CH2:12][NH:13][CH2:14]2)[CH2:10]1)=[O:8].Cl[C:24]1[C:29]([CH3:30])=[N:28][C:27]([CH3:31])=[CH:26][N:25]=1>>[C:1]1([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]([N:9]1[CH2:10][CH:11]2[CH:15]([CH2:14][N:13]([C:24]3[C:29]([CH3:30])=[N:28][C:27]([CH3:31])=[CH:26][N:25]=3)[CH2:12]2)[CH2:16]1)=[O:8]

Participants

3

Reactant 2

HCID 116726802-Chloro-3,5-dimethylpyrazineHCID 67116416Biphenyl-2-yl-(hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-methanone

Product 1

HCID 52917387HCID 52917387, compound

Procedure

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 17 and 2-chloro-3,5-dimethyl-pyrazine. MS (ESI) mass calcd. for C25H26N4O, 398.50; m/z found, 399.2 [M+H]+.

Sources & evidence

ORD record
ord-d304050f6bb24ffb854519f05deabe64
Source dataset
uspto-grants-2014_02
Patent number
US08653263B2

Reaction notes

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