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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 243963Generated: October 31, 2026

2-Chloro-6-(trifluoromethyl)pyridine → HCID 67116632, compound

https://huagongshe.com/reaction/243963

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-6-(trifluoromethyl)pyridineHCID 602334—
Reactant(Hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-(2-thiophen-2-yl-phenyl)-methanoneHCID 67116155—
ProductHCID 67116632HCID 67116632—

Reaction Steps

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 37 and 2-chloro-6-trifluoromethyl-pyridine. MS (ESI): mass calculated for C23H20F3N3OS, 443.49; m/z found 444.1 [M+H]+. 1H NMR (400 MHz, CDCl3): 7.62-7.33 (m, 5H), 7.29-7.05 (m, 2H), 7.04-6.80 (m, 2H), 6.37 (s, 1H), 4.01-2.47 (m, 10H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08653263B2
Source datasetuspto-grants-2014_02
ORD IDord-cf9c1af772204e3ea1cf499560e891b4
Source noteuspto-grants-2014_02