6-Chloro-2-picoline → HCID 67116905, compound

Participants

Role	Name	HCID	Charge
Reactant	6-Chloro-2-picoline	HCID 87601	—
Reactant	(Hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-(2-thiophen-2-yl-phenyl)-methanone	HCID 67116155	—
Product	HCID 67116905	HCID 67116905	—

Reaction Steps

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 37 and 2-chloro-6-methyl-pyridine. MS (ESI): mass calculated for C23H23N3OS, 389.52; m/z found 390.2 [M+H]+. 1H NMR (400 MHz, CDCl3): 7.56-7.47 (m, 1H), 7.45-7.10 (m, 6H), 7.07-6.91 (m, 1H), 6.43 (d, J=7.2, 1H), 6.04 (s, 1H), 3.96-2.57 (m, 10H), 2.38 (s, 3H).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08653263B2
Source dataset	uspto-grants-2014_02
ORD ID	ord-793b66d663884d57b4537295039c1e66
Source note	uspto-grants-2014_02