o-Phenylbenzoic acid → HCID 67116530, compound

HRID 243973Notes

Reaction equation

HRID 243973 reaction equation
[C:1]1([C:7]2[CH:12]=[CH:11][N:10]=[C:9]([N:13]3[CH2:20][CH:19]4[CH:15]([CH2:16][NH:17][CH2:18]4)[CH2:14]3)[N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:21]1([C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)[C:22]([C:27](O)=[O:28])=[CH:23][CH:24]=[CH:25][CH:26]=1>>[C:21]1([C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[C:27]([N:17]1[CH2:16][CH:15]2[CH:19]([CH2:20][N:13]([C:9]3[N:8]=[C:7]([C:1]4[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=4)[CH:12]=[CH:11][N:10]=3)[CH2:14]2)[CH2:18]1)=[O:28]

Participants

3

Reactant 2

HCID 70357o-Phenylbenzoic acidHCID 699390982-(4-Phenyl-pyrimidin-2-yl)-octahydro-pyrrolo[3,4-c]pyrrole

Product 1

HCID 67116530HCID 67116530, compound

Procedure

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 26 and biphenyl-2-carboxylic acid. MS (ESI) mass calcd. for C29H26N4O, 446.56; m/z found, 447.3 [M+H]+.

Sources & evidence

ORD record
ord-c72ff4d44a26459cb6bc26892f93d185
Source dataset
uspto-grants-2014_02
Patent number
US08653263B2

Reaction notes

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