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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 243982Generated: October 27, 2026

6-Chloro-2-picoline → 2-(Biphenyl-2-ylcarbonyl)-5-(6-methylpyridin-2-yl)octahydropyrrolo[3,4-c]pyrrole

https://huagongshe.com/reaction/243982

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Chloro-2-picolineHCID 87601—
ReactantBiphenyl-2-yl-(hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-methanoneHCID 67116416—
Product2-(Biphenyl-2-ylcarbonyl)-5-(6-methylpyridin-2-yl)octahydropyrrolo[3,4-c]pyrroleHCID 67116353—

Reaction Steps

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 17 and 2-chloro-6-methyl-pyridine. MS (ESI) mass calcd. for C25H25N43O, 383.5; m/z found, 384.3 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08653263B2
Source datasetuspto-grants-2014_02
ORD IDord-e00248cdb29b44f9a5398b77ded646e5
Source noteuspto-grants-2014_02