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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 243983Generated: October 27, 2026

2-Chloro-4-methylpyrimidine → 2-(Biphenyl-2-ylcarbonyl)-5-(4-methylpyrimidin-2-yl)octahydropyrrolo[3,4-c]pyrrole

https://huagongshe.com/reaction/243983

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-4-methylpyrimidineHCID 11629607—
ReactantBiphenyl-2-yl-(hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-methanoneHCID 67116416—
Product2-(Biphenyl-2-ylcarbonyl)-5-(4-methylpyrimidin-2-yl)octahydropyrrolo[3,4-c]pyrroleHCID 67117015—

Reaction Steps

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 17 and 2-chloro-4-methyl-pyrimidine. MS (ESI) mass calcd. for C24H24N4O, 384.49; m/z found, 385.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08653263B2
Source datasetuspto-grants-2014_02
ORD IDord-eb8810e5ab924a3abfb316d951a6d069
Source noteuspto-grants-2014_02