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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 243987Generated: October 25, 2026

2-Chloro-4-methylquinoline → 2-[5-(Biphenyl-2-ylcarbonyl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl]-4-methylquinoline

https://huagongshe.com/reaction/243987

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-4-methylquinolineHCID 69449—
ReactantBiphenyl-2-yl-(hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-methanoneHCID 67116416—
Product2-[5-(Biphenyl-2-ylcarbonyl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl]-4-methylquinolineHCID 67116311—

Reaction Steps

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 17 and 2-chloro-4-methyl-quinoline. MS (ESI) mass calcd. for C29H27N3O, 433.56; m/z found, 434.3 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08653263B2
Source datasetuspto-grants-2014_02
ORD IDord-b089b105c4e842ddadcdcf8e403eb5ce
Source noteuspto-grants-2014_02