2-Chlorobenzoxazole → HCID 67116332, compound

HRID 243990Notes

Reaction equation

HRID 243990 reaction equation
[C:1]1([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]([N:9]1[CH2:16][CH:15]2[CH:11]([CH2:12][NH:13][CH2:14]2)[CH2:10]1)=[O:8].Cl[C:24]1[O:25][C:26]2[CH:32]=[CH:31][CH:30]=[CH:29][C:27]=2[N:28]=1>>[O:25]1[C:26]2[CH:32]=[CH:31][CH:30]=[CH:29][C:27]=2[N:28]=[C:24]1[N:13]1[CH2:14][CH:15]2[CH2:16][N:9]([C:7]([C:2]3[CH:3]=[CH:4][CH:5]=[CH:6][C:1]=3[C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)=[O:8])[CH2:10][CH:11]2[CH2:12]1

Participants

3

Reactant 2

HCID 119862-ChlorobenzoxazoleHCID 67116416Biphenyl-2-yl-(hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-methanone

Product 1

HCID 67116332HCID 67116332, compound

Procedure

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 17 and 2-chloro-benzooxazole. MS (ESI): mass calculated for C26H23N3O2, 409.49; m/z found 410.2 [M+H]+.

Sources & evidence

ORD record
ord-2f4d20ec3292405fa5a52f23d17d5b46
Source dataset
uspto-grants-2014_02
Patent number
US08653263B2

Reaction notes

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