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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 243991Generated: October 30, 2026

6-Chloro-2-picoline → (2,4-Dimethoxy-phenyl)-[5-(6-methyl-pyridin-2-yl)-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl]-methanone

https://huagongshe.com/reaction/243991

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Chloro-2-picolineHCID 87601—
Reactant(2,4-Dimethoxy-phenyl)-(hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-methanoneHCID 66211208—
Product(2,4-Dimethoxy-phenyl)-[5-(6-methyl-pyridin-2-yl)-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl]-methanoneHCID 67116151—

Reaction Steps

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 38 and 2-chloro-6-methyl-pyridine. MS (ESI): mass calculated for C21H25N3O3, 367.45; m/z found 368.3 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08653263B2
Source datasetuspto-grants-2014_02
ORD IDord-6e10a0517cc642e6ad8b14b0b56402e4
Source noteuspto-grants-2014_02