2-Chlorobenzoxazole → HCID 67116947, compound

HRID 243996Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([O:9][CH3:10])[C:4]=1[C:11]([N:13]1[CH2:20][CH:19]2[CH:15]([CH2:16][NH:17][CH2:18]2)[CH2:14]1)=[O:12].Cl[C:22]1[O:23][C:24]2[CH:30]=[CH:29][CH:28]=[CH:27][C:25]=2[N:26]=1>>[O:23]1[C:24]2[CH:30]=[CH:29][CH:28]=[CH:27][C:25]=2[N:26]=[C:22]1[N:17]1[CH2:16][CH:15]2[CH2:14][N:13]([C:11]([C:4]3[C:3]([O:2][CH3:1])=[CH:8][CH:7]=[CH:6][C:5]=3[O:9][CH3:10])=[O:12])[CH2:20][CH:19]2[CH2:18]1

Participants

Reactant 2

HCID 119862-Chlorobenzoxazole

HCID 66212560HCID 66212560, compound

Product 1

HCID 67116947HCID 67116947, compound

Procedure

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 41 and 2-chloro-benzooxazole. MS (ESI): mass calculated for C22H23N3O4, 393.45; m/z found 394.2 [M+H]+.

Sources & evidence

ORD record: ord-f3b8fd969ce14c3d9b86e2daf709af57
Source dataset: uspto-grants-2014_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08653263B2

Reaction notes

Loading…