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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 244002Generated: October 30, 2026

2-(3-chlorophenyl)benzoic Acid → (3'-Chloro-biphenyl-2-yl)-[5-(4-phenyl-pyrimidin-2-yl)-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl]-methanone

https://huagongshe.com/reaction/244002

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-chlorophenyl)benzoic AcidHCID 2757415—
Reactant2-(4-Phenyl-pyrimidin-2-yl)-octahydro-pyrrolo[3,4-c]pyrroleHCID 69939098—
Product(3'-Chloro-biphenyl-2-yl)-[5-(4-phenyl-pyrimidin-2-yl)-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl]-methanoneHCID 67117180—

Reaction Steps

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 26 and 3′-chloro-biphenyl-2-carboxylic acid. MS (ESI): mass calculated for C29H25ClN4O, 480.99; m/z found 481.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08653263B2
Source datasetuspto-grants-2014_02
ORD IDord-01495881dc584211ad3332e7f22bf796
Source noteuspto-grants-2014_02