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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 244003Generated: November 2, 2026

2-Methoxybenzoic acid → (2-Methoxy-phenyl)-[5-(4-methyl-pyrimidin-2-yl)-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl]-methanone

https://huagongshe.com/reaction/244003

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methoxybenzoic acidHCID 11370—
Reactant2-(4-Methyl-pyrimidin-2-yl)-octahydro-pyrrolo[3,4-c]pyrroleHCID 64458966—
Product(2-Methoxy-phenyl)-[5-(4-methyl-pyrimidin-2-yl)-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl]-methanoneHCID 67116351—

Reaction Steps

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 27 and 2-methoxybenzoic acid. MS (ESI): mass calculated for C19H22N4O2, 338.41; m/z found 339.3 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08653263B2
Source datasetuspto-grants-2014_02
ORD IDord-3adaa96d386642bc8d09f28099f7eb73
Source noteuspto-grants-2014_02