3-Fluoro-2-(2H-1,2,3-triazol-2-yl)benzoic acid → HCID 67116413, compound

Participants

Role	Name	HCID	Charge
Reactant	3-Fluoro-2-(2H-1,2,3-triazol-2-yl)benzoic acid	HCID 67086549	—
Reactant	2-(4,5,6-Trimethylpyrimidin-2-yl)octahydropyrrolo[3,4-c]pyrrole	HCID 69939398	—
Product	HCID 67116413	HCID 67116413	—

Reaction Steps

The title compound was prepared in a manner analogous to Example 15, utilizing Intermediate 42 and 3-fluoro-2-(2H-1,2,3-triazol-2-yl)benzoic acid. MS (ESI): mass calculated for C22H24FN7O, 421.20; m/z found 422.2 [M+H]+. 1H NMR (500 MHz, CDCl3): 7.82-7.77 (m, 2H), 7.51-7.44 (m, 1H), 7.31 (ddd, J=9.8, 8.4, 1.3, 1H), 7.25-7.20 (m, 1H), 3.86-3.60 (m, 3H), 3.59-3.42 (m, 4H), 3.14 (dd, J=10.9, 5.3, 1H), 2.94 (dd, J=10.9, 7.1, 2H), 2.38-2.27 (m, 6H), 2.07 (d, J=7.2, 3H).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08653263B2
Source dataset	uspto-grants-2014_02
ORD ID	ord-5c1e5791094447a886367928f7678c87
Source note	uspto-grants-2014_02