2-Phenylbenzene-1-sulfonyl chloride → 2-(5-([1,1'-biphenyl]-2-ylsulfonyl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)quinoxaline
Reaction equation
[C:1]1([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:2]([S:7](Cl)(=[O:9])=[O:8])=[CH:3][CH:4]=[CH:5][CH:6]=1.[CH2:17]1[CH:21]2[CH2:22][NH:23][CH2:24][CH:20]2[CH2:19][N:18]1[C:25]1[CH:34]=[N:33][C:32]2[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=2)[N:26]=1>>[C:1]1([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[S:7]([N:23]1[CH2:22][CH:21]2[CH2:17][N:18]([C:25]3[CH:34]=[N:33][C:32]4[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=4)[N:26]=3)[CH2:19][CH:20]2[CH2:24]1)(=[O:9])=[O:8]Participants
3
Procedure
The title prophetic compound may be synthesized using biphenylsulfonylchloride and Intermediate 35. MS (ESI) mass calcd. for C26H24N4O2S, 456.16.
Workup
- customThe title prophetic compound may be synthesized
Sources & evidence
- ORD record
- ord-24480ce30c914da4b3aa6216055bc08e
- Source dataset
- uspto-grants-2014_02
- Patent number
- US08653263B2
Reaction notes
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