Oxindole → 3-(6-Methoxybiphenyl-3-ylmethylene)-1,3-dihydroindol-2-one

HRID 24417Notes

Reaction equation

HRID 24417 reaction equation
[CH3:1][O:2][C:3]1[CH:10]=[CH:9][C:6]([CH:7]=O)=[CH:5][C:4]=1[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1.[NH:17]1[C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[CH2:19][C:18]1=[O:26]>>[CH3:1][O:2][C:3]1[C:4]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:5][C:6]([CH:7]=[C:19]2[C:20]3[C:25](=[CH:24][CH:23]=[CH:22][CH:21]=3)[NH:17][C:18]2=[O:26])=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 321710OxindoleHCID 223912176-Methoxybiphenyl-3-carbaldehyde

Product 1

HCID 544662923-(6-Methoxybiphenyl-3-ylmethylene)-1,3-dihydroindol-2-one

Procedure

4-Methoxy-3-phenylbenzaldehyde was condensed with 2-oxindole to give 0.3 g of 3-(6-methoxybiphenyl-3-ylmethylene)-1,3-dihydroindol-2-one as a yellow-orange solid.

Sources & evidence

ORD record
ord-3d88ccf0cdbf46d3a3cf82d992bf4bee
Source dataset
uspto-grants-2005_02
Patent number
US06855730B2

Reaction notes

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