1,3-Dihydro-2H-pyrrolo(2,3-b)pyridin-2-one → 3-(3-Cyclohexyl-4-methoxybenzylidene)-1,3-dihydropyrrolo[2,3-b]pyridin-2-one

HRID 24424Notes

Reaction equation

HRID 24424 reaction equation
[CH:1]1([C:7]2[CH:8]=[C:9]([CH:12]=[CH:13][C:14]=2[O:15][CH3:16])[CH:10]=O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[NH:17]1[C:25]2[C:20](=[CH:21][CH:22]=[CH:23][N:24]=2)[CH2:19][C:18]1=[O:26]>>[CH:1]1([C:7]2[CH:8]=[C:9]([CH:12]=[CH:13][C:14]=2[O:15][CH3:16])[CH:10]=[C:19]2[C:20]3[C:25](=[N:24][CH:23]=[CH:22][CH:21]=3)[NH:17][C:18]2=[O:26])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 138640951,3-Dihydro-2H-pyrrolo(2,3-b)pyridin-2-oneHCID 225711053-Cyclohexyl-4-methoxybenzaldehyde

Product 1

HCID 542975213-(3-Cyclohexyl-4-methoxybenzylidene)-1,3-dihydropyrrolo[2,3-b]pyridin-2-one

Procedure

3-Cyclohexyl-4-methoxybenzaldehyde was condensed with 7-aza-2-oxindole to give 0.25 g of 3-(3-Cyclohexyl-4-methoxy-benzylidene)-1,3-dihydropyrrolo[2,3-b]pyridin-2-one as a yellow-orange solid.

Sources & evidence

ORD record
ord-794a993edcfd4b51a39cab61dd680ea7
Source dataset
uspto-grants-2005_02
Patent number
US06855730B2

Reaction notes

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