2,3-Dihydrobenzofuran-5-carboxaldehyde → HCID 69764879, compound

HRID 24425Notes

Reaction equation

HRID 24425 reaction equation
[CH:1]([C:3]1[CH:4]=[CH:5][C:6]2[O:10][CH2:9][CH2:8][C:7]=2[CH:11]=1)=O.[NH:12]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][N:19]=2)[CH2:14][C:13]1=[O:21]>>[O:10]1[C:6]2[CH:5]=[CH:4][C:3]([CH:1]=[C:14]3[C:15]4[C:20](=[N:19][CH:18]=[CH:17][CH:16]=4)[NH:12][C:13]3=[O:21])=[CH:11][C:7]=2[CH2:8][CH2:9]1

Participants

3

Reactant 2

HCID 7359012,3-Dihydrobenzofuran-5-carboxaldehydeHCID 138640951,3-Dihydro-2H-pyrrolo(2,3-b)pyridin-2-one

Product 1

HCID 69764879HCID 69764879, compound

Procedure

2,3-Dihydro-5-formylbenzofuran (commercially available) was condensed with 7-aza-2-oxindole to give 0.2 g of 3-(2,3-dihydrobenzofuran-5-ylmethylene)-1,3-dihydropyrrolo[2,3-b]pyridin-2-one as a yellow-orange solid.

Sources & evidence

ORD record
ord-c1581d8a7b5e4a14b4f8b4e6a91a5cdb
Source dataset
uspto-grants-2005_02
Patent number
US06855730B2

Reaction notes

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