6-Trifluoromethyloxindole → HCID 54490013, compound

HRID 24433Notes

Reaction equation

HRID 24433 reaction equation
[CH:1]([C:4]1[CH:5]=[C:6]([CH:9]=[C:10]([CH:14]([CH3:16])[CH3:15])[C:11]=1[O:12][CH3:13])[CH:7]=O)([CH3:3])[CH3:2].[F:17][C:18]([F:30])([F:29])[C:19]1[CH:27]=[C:26]2[C:22]([CH2:23][C:24](=[O:28])[NH:25]2)=[CH:21][CH:20]=1>>[CH:1]([C:4]1[CH:5]=[C:6]([CH:9]=[C:10]([CH:14]([CH3:16])[CH3:15])[C:11]=1[O:12][CH3:13])[CH:7]=[C:23]1[C:22]2[C:26](=[CH:27][C:19]([C:18]([F:30])([F:29])[F:17])=[CH:20][CH:21]=2)[NH:25][C:24]1=[O:28])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 6084876-TrifluoromethyloxindoleHCID 105850253,5-Diisopropyl-4-methoxybenzaldehyde

Product 1

HCID 54490013HCID 54490013, compound

Procedure

3,5-Diisopropyl-4-methoxybenzaldehyde was condensed with 6-trifluoromethyl-2-oxindole to give 0.35 g of 3-(3,5-diisopropyl-4-methoxybenzylidene)-6-trifluoromethyl-1,3-dihydroindol-2-one as a yellow-orange solid.

Sources & evidence

ORD record
ord-7a2cb751652d4fb28f77f663fd56633b
Source dataset
uspto-grants-2005_02
Patent number
US06855730B2

Reaction notes

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