Aluminium lithium hydride → HCID 24960188, compound

Participants

Reaction Steps

To a solution of 66 mg (0.17 mmol) of [1-(4-fluorophenyl)-1H-indazol-5-yl]-((E)-2-phenyl-1-trifluoromethylvinyl)amine in THF was added 10 mg (0.26 mmol) of lithium aluminum hydride. The mixture stirred for 2 hours at room temperature and was then quenched with saturated aqueous sodium sulfate and extracted with EtOAc. The organic layer was washed with brine, dried over sodium sulfate and concentrated. The crude was purified by prep. TLC using 100% dichloromethane to provide 10 mg (7%) of the title compound as a yellow solid. MS m/z 400 (MH+).

Provenance & Evidence