2-oxo-2,3-dihydro-1H-indole-4-carboxylic acid → 3-(3,5-diisopropyl-4-methoxybenzylidene)-2-oxo-2,3-dihydro-1H-indole-4-carboxylic acid

HRID 24443Notes

Reaction equation

HRID 24443 reaction equation
[CH:1]([C:4]1[CH:5]=[C:6]([CH:9]=[C:10]([CH:14]([CH3:16])[CH3:15])[C:11]=1[O:12][CH3:13])[CH:7]=O)([CH3:3])[CH3:2].[C:17]([C:20]1[CH:28]=[CH:27][CH:26]=[C:25]2[C:21]=1[CH2:22][C:23](=[O:29])[NH:24]2)([OH:19])=[O:18]>>[CH:1]([C:4]1[CH:5]=[C:6]([CH:9]=[C:10]([CH:14]([CH3:16])[CH3:15])[C:11]=1[O:12][CH3:13])[CH:7]=[C:22]1[C:21]2[C:20]([C:17]([OH:19])=[O:18])=[CH:28][CH:27]=[CH:26][C:25]=2[NH:24][C:23]1=[O:29])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 103973292-oxo-2,3-dihydro-1H-indole-4-carboxylic acidHCID 105850253,5-Diisopropyl-4-methoxybenzaldehyde

Product 1

HCID 539392423-(3,5-diisopropyl-4-methoxybenzylidene)-2-oxo-2,3-dihydro-1H-indole-4-carboxylic acid

Procedure

3,5-Diisopropyl-4-methoxybenzaldehyde was condensed with 4-carboxy-2-oxindole to give 0.3 g of 3-(3,5-diisopropyl-4-methoxybenzylidene)-2-oxo-2,3-dihydro-1H-indole-4-carboxylic acid as a yellow-orange solid.

Sources & evidence

ORD record
ord-891be8e7bd4249dda69ef633b578898c
Source dataset
uspto-grants-2005_02
Patent number
US06855730B2

Reaction notes

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