4-Methyl-1,3-dihydro-2H-indol-2-one → 3-(6-Methoxybiphenyl-3-ylmethylene)-4-methyl-1,3-dihydroindol-2-one

HRID 24448Notes

Reaction equation

HRID 24448 reaction equation
[CH3:1][O:2][C:3]1[CH:10]=[CH:9][C:6]([CH:7]=O)=[CH:5][C:4]=1[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1.[CH3:17][C:18]1[CH:26]=[CH:25][CH:24]=[C:23]2[C:19]=1[CH2:20][C:21](=[O:27])[NH:22]2>>[CH3:1][O:2][C:3]1[C:4]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:5][C:6]([CH:7]=[C:20]2[C:19]3[C:23](=[CH:24][CH:25]=[CH:26][C:18]=3[CH3:17])[NH:22][C:21]2=[O:27])=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 125793824-Methyl-1,3-dihydro-2H-indol-2-oneHCID 223912176-Methoxybiphenyl-3-carbaldehyde

Product 1

HCID 544100543-(6-Methoxybiphenyl-3-ylmethylene)-4-methyl-1,3-dihydroindol-2-one

Procedure

4-Methoxy-3-phenylbenzaldehyde was condensed with 4-methyl-2-oxindole to give 0.3 g of 3-(6-methoxybiphenyl-3-ylmethylene)-4-methyl-1,3-dihydroindol-2-one as a yellow-orange solid.

Sources & evidence

ORD record
ord-4cc77ca1bb85416d9ccf58110ebff71e
Source dataset
uspto-grants-2005_02
Patent number
US06855730B2

Reaction notes

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