Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Formamide | HCID 713 | — |
| Edukt | Water | HCID 962 | — |
| Edukt | 3-amino-5-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile | HCID 22346784 | — |
| Produkt | HCID 178508717 | HCID 178508717 | — |
Reaktionsschritte
3-Amino-4-cyano-5-(4-phenoxyphenyl)pyrazole (29.5 g) is suspended in formamide (300 mL) and heated under nitrogen at 180° C. for 4 hours. The reaction mixture is cooled to 30° C. and water (300 mL) is added. The solid is collected, washed well with water, then with methanol and dried in air to give of 4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US08658653B2 |
|---|
| Quelldatensatz | uspto-grants-2014_02 |
|---|
| ORD ID | ord-d3c5af1e8f124d2e8125b518d2e957c6 |
|---|
| Quellennotiz | uspto-grants-2014_02 |
|---|
