5-Chloro-4-methylindolin-2-one → 5-Chloro-3-(3,5-diisopropyl-4-methoxybenzylidene)-4-methyl-1,3-dihydroindol-2-one

HRID 24452Notes

Reaction equation

HRID 24452 reaction equation
[CH:1]([C:4]1[CH:5]=[C:6]([CH:9]=[C:10]([CH:14]([CH3:16])[CH3:15])[C:11]=1[O:12][CH3:13])[CH:7]=O)([CH3:3])[CH3:2].[CH3:17][C:18]1[C:26]([Cl:27])=[CH:25][CH:24]=[C:23]2[C:19]=1[CH2:20][C:21](=[O:28])[NH:22]2>>[Cl:27][C:26]1[C:18]([CH3:17])=[C:19]2[C:23](=[CH:24][CH:25]=1)[NH:22][C:21](=[O:28])[C:20]2=[CH:7][C:6]1[CH:5]=[C:4]([CH:1]([CH3:3])[CH3:2])[C:11]([O:12][CH3:13])=[C:10]([CH:14]([CH3:16])[CH3:15])[CH:9]=1

Participants

3

Reactant 2

HCID 103133885-Chloro-4-methylindolin-2-oneHCID 105850253,5-Diisopropyl-4-methoxybenzaldehyde

Product 1

HCID 540727365-Chloro-3-(3,5-diisopropyl-4-methoxybenzylidene)-4-methyl-1,3-dihydroindol-2-one

Procedure

3,5-Diisopropyl-4-methoxybenzaldehyde was condensed with 4-methyl-5-chloro-2-oxindole to give 0.4 g of 5-chloro-3-(3,5-diisopropyl-4-methoxybenzylidene)-4-methyl-1,3-dihydroindol-2-one as a yellow-orange solid.

Sources & evidence

ORD record
ord-e3009d255d574fe69a033550133d28f2
Source dataset
uspto-grants-2005_02
Patent number
US06855730B2

Reaction notes

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