HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 244620Generated: October 31, 2026
Chlorosuccinimide → HCID 58356372, compound
https://huagongshe.com/reaction/244620
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Chlorosuccinimide | HCID 31398 | — |
| Reactant | Methyl 1-isopropyl-1H-pyrazole-5-carboxylate | HCID 19576656 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 58356372 | HCID 58356372 | 93.6% |
Reaction Steps
A solution of methyl 1-(1-methylethyl)-1H-pyrazole-5-carboxylate (120 mg) in DMF (3 ml) was treated with N-chlorosuccinimide (95 mg) and heated to 60° C. for 18 h under nitrogen. The cooled mixture was partitioned between diethyl ether (20 ml) and water (20 ml), separated and dried over sodium sulphate then evaporated to give the title compound as a pale yellow oil (135 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08658635B2 |
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| Source dataset | uspto-grants-2014_02 |
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| ORD ID | ord-d39ab63f79d640aeacf1427efdfa433b |
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| Source note | uspto-grants-2014_02 |
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