HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 244685Generated: October 29, 2026
Thionyl Chloride → 1-Isopropyl-1H-pyrazole-5-carbonyl chloride
https://huagongshe.com/reaction/244685
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 1-(propan-2-yl)-1H-pyrazole-5-carboxylic acid | HCID 3150947 | — |
| Product | 1-Isopropyl-1H-pyrazole-5-carbonyl chloride | HCID 58356422 | — |
Reaction Steps
Thionyl chloride (5 ml) was added to 1-(1-methylethyl)-1H-pyrazole-5-carboxylic acid (1 g) and the reaction was heated at 80° C. for 5 h. The reaction was evaporated, then azeotroped with toluene to give title compound, 856 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08658635B2 |
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| Source dataset | uspto-grants-2014_02 |
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| ORD ID | ord-270bd04e4d5e40fc80dfaf99e709ba8c |
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| Source note | uspto-grants-2014_02 |
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