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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 24475Generated: October 25, 2026

N-methyl-2-oxoindoline-5-sulfonamide → 4-(3-dimethylaminopropyl)-2-methyl-5-(5-methylsulfamoyl-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-1H-pyrrole-3-carboxylic acid

https://huagongshe.com/reaction/24475

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-methyl-2-oxoindoline-5-sulfonamideHCID 10176909—
Reactant4-(3-dimethylaminopropyl)-5-formyl-2-methyl-1H-pyrrole-3-carboxylic acidHCID 22571074—
Product4-(3-dimethylaminopropyl)-2-methyl-5-(5-methylsulfamoyl-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-1H-pyrrole-3-carboxylic acidHCID 5414950322.4%

Reaction Steps

2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid methylamide (113 mg) was condensed with 4-(3-dimethylaminopropyl)-5-formyl-2-methyl-1H-pyrrole-3-carboxylic acid (119 mg) to give 50 mg 4-(3-dimethylaminopropyl)-2-methyl-5-(5-methylsulfamoyl-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-1H-pyrrole-3-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06855730B2
Source datasetuspto-grants-2005_02
ORD IDord-9053dda97a26429d9d87388cdc5e7a24
Source noteuspto-grants-2005_02