HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloro-o-cresol → 3-Chloro-4-hydroxy-5-methylbenzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloro-o-cresol | HCID 6898 | — |
| Reactant | 3-Ethyl-4-hydroxy-5-methylbenzonitrile | HCID 59759950 | — |
| Product | 3-Chloro-4-hydroxy-5-methylbenzonitrile | HCID 19038348 | — |
Reaction Steps
The title compound is prepared from commercially available 2-chloro-6-methyl-phenol in analogy to literature procedures (see 3-ethyl-4-hydroxy-5-methyl-benzonitrile); LC-MS: tR=0.85 min. 1H NMR (CDCl3): δ2.33 (s, 3H), 6.10 (s, 1H), 7.38 (s, 1H), 7.53 (d, J=1.8 Hz, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08658675B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-e292915cc695425ba70d52795a618835 |
| Source note | uspto-grants-2014_02 |