alpha-Chlorohydrin, (+)- → HCID 49871975, compound

Participants

Reaction Steps

The title compound is prepared in analogy to Example 3 starting from 2-cyclohexyl-6-methoxy-isonicotinic acid, 3-ethyl-4,N-dihydroxy-5-methyl-benzamidine and (S)-3-chloro-1,2-propanediol; LC-MS: tR=1.16 min, [M+H]+=468.08; 1H NMR (CDCl3): δ1.33 (t, J=7.5 Hz, 3H), 1.34-1.40 (m, 1H), 1.40-1.52 (m, 2H), 1.57-1.69 (m, 2H), 1.77-1.84 (m, 1H), 1.87-1.95 (m, 2H), 1.99-2.08 (m, 2H), 2.41 (s, 3H), 2.70-2.81 (m, 3H), 3.83-4.00 (m, 4H), 4.03 (s, 3H), 4.15-4.21 (m, 1H), 7.32 (s, 1H), 7.49 (s, 1H), 7.88 (s, 1H), 7.90 (s, 1H).

Provenance & Evidence