反应详情

A suspension of 3 g of 5-chlorosulfonyl-2-oxindole, 1.15 g of isopropylamine and 1.2 mL of pyridine in 50 mL of dichloromethane was stirred at room temperature for 4 hours at which time a white solid was present. The solid was collected by vacuum filtration, slurry-washed with hot ethanol, cooled, collected by vacuum filtration and vacuum dried at 40° C. to give 1.5 g (45%) of 5-isopropylaminosulfonyl-2-oxindole.

1. filtrationThe solid was collected by vacuum filtration
2. washslurry-washed with hot ethanol
3. temperaturecooled
4. filtrationcollected by vacuum filtration and vacuum
5. customdried at 40° C.