HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 245311Generated: October 26, 2026
Dibenzylamine → (S)-1-chloro-3-(dibenzylamino)propan-2-ol
https://huagongshe.com/reaction/245311
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dibenzylamine | HCID 7656 | — |
| Reactant | Lithium Bromide | HCID 82050 | — |
| Reactant | (+)-Epichlorohydrin | HCID 149428 | — |
| Product | (S)-1-chloro-3-(dibenzylamino)propan-2-ol | HCID 49765557 | 91.4% |
Reaction Steps
Dibenzylamine (39.4 g, 0.20 mol) and lithium bromide (1.7 g, 20 mmol) were added to (S)-epichlorohydrin (185 g, 2 mol). The mixture was stirred at room temperature (25° C.) for 2 hours, Filtered, and the solvent was evaporated to provide 53 g of colorless Oil in 90% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08658789B2 |
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| Source dataset | uspto-grants-2014_02 |
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| ORD ID | ord-bc67d106fc274d61bdafe7d7a5e4cd11 |
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| Source note | uspto-grants-2014_02 |
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