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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 245436Generated: November 1, 2026

(2R,6S)-4-(2-((tert-Butyldiphenylsilyloxy)methyl)-4-chloro-5-fluoropyridin-3-yl)-2,6-dimethylmorpholine → HCID 67358545, compound

https://huagongshe.com/reaction/245436

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2R,6S)-4-(2-((tert-Butyldiphenylsilyloxy)methyl)-4-chloro-5-fluoropyridin-3-yl)-2,6-dimethylmorpholineHCID 67319975—
ReactantHCID 86717864HCID 86717864—
ProductHCID 67358545HCID 67358545—

Reaction Steps

Starting material: (2R,6S)-4-(2-((tert-butyldiphenylsilyloxy)methyl)-4-chloro-5-fluoropyridin-3-yl)-2,6-dimethylmorpholine (Intermediate 45) and 6-cyano-N-methoxy-N-methylnicotinamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08658641B2
Source datasetuspto-grants-2014_02
ORD IDord-76f1383217fc485e8d300819920e7ea0
Source noteuspto-grants-2014_02