Benzylamine → 3-(Benzylamino)-1,1,1-trifluoropropan-2-ol

HRID 245516Notes

Reaction equation

[CH2:1]([NH2:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:9][C:10]([F:15])([F:14])[CH:11]1[CH2:13][O:12]1>>[CH2:1]([NH:8][CH2:13][CH:11]([OH:12])[C:10]([F:15])([F:14])[F:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 7504Benzylamine

HCID 5207692-(Trifluoromethyl)oxirane

Product 1

HCID 37877943-(Benzylamino)-1,1,1-trifluoropropan-2-ol

Procedure

Starting material: benzylamine and 2-(trifluoromethyl)oxirane

Sources & evidence

ORD record: ord-72a0ed4de4964b35bec4b347589b987a
Source dataset: uspto-grants-2014_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08658641B2

Reaction notes

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