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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 245533Generated: October 30, 2026

trans-2,6-Dimethylmorpholine → 6-((2R,6R)-2,6-dimethylmorpholino)-7-fluoro-3-methylbenzo[d]isoxazole-5-carbaldehyde

https://huagongshe.com/reaction/245533

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttrans-2,6-DimethylmorpholineHCID 11137133—
ReactantHCID 86658113HCID 86658113—
Product6-((2R,6R)-2,6-dimethylmorpholino)-7-fluoro-3-methylbenzo[d]isoxazole-5-carbaldehydeHCID 86658123—

Reaction Steps

Starting materials: 6,7-difluoro-3-methylbenzo[d]isoxazole-5-carbaldehyde (Intermediate 374) and (2R,6R)-2,6-dimethylmorpholine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08658641B2
Source datasetuspto-grants-2014_02
ORD IDord-a0454f03af7340648f1ccfa2532e31c6
Source noteuspto-grants-2014_02