4-(Methylimino)cyclohexanone ketal → 4-Methylamino-4-phenylcyclohexanone

Participants

Reaction Steps

N-(1,4-dioxaspiro[4,5]-decan-8-yliden)-methanamine (43 g, 0.25 mol) was dissolved in dibutyl ether (75 ml) and added at room temperature (15-32° C.) to a solution of phenyllithium in dibutyl ether (1.8 M, 149 ml, 0.27 mol). The batch was stirred at room temperature for 1 h.

Provenance & Evidence