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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 245678Generated: October 30, 2026

2-Methoxyethylamine → N-((3-chloropyrazin-2-yl)methyl)-4-(2-methoxyethylamino)cyclohexanecarboxamide

https://huagongshe.com/reaction/245678

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MethoxyethylamineHCID 8018—
ReactantN-((3-chloropyrazin-2-yl)methyl)-4-oxocyclohexanecarboxamideHCID 86674630—
ProductN-((3-chloropyrazin-2-yl)methyl)-4-(2-methoxyethylamino)cyclohexanecarboxamideHCID 8667464294.2%

Reaction Steps

Using the procedure described in example 7 step 7a N-((3-chloropyrazin-2-yl)methyl)-4-oxocyclo-hexanecarboxamide (1 g) and 2-methoxyethanamine (0.281 g) gave N-((3-chloropyrazin-2-yl)methyl)-4-(2-methoxyethylamino)cyclohexanecarboxamide (1.15 g, mixture of cis and trans).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08658794B2
Source datasetuspto-grants-2014_02
ORD IDord-860ebcd832474f999fa404fcf2de3e9e
Source noteuspto-grants-2014_02