Trifluoroacetic acid → HCID 71280269, compound

Participants

Reaction Steps

In a round-bottomed flask, ((R)-2,2-difluoro-1-methyl-3-phenyl-propyl)-carbamic acid tert-butyl ester (92 mg, 0.32 mmol) was dissolved in dichloromethane (2 ml) and trifluoroacetic acid (0.75 ml, 9.73 mmol) was slowly added. The reaction was stirred at room temperature for 2 h then concentrated to give (R)-2,2-difluoro-1-methyl-3-phenyl-propylamine trifluoroacetate as a light brown oil which was used without further purification

Provenance & Evidence