Hydrochloric Acid → (R)-1-(furan-2-yl)ethan-1-amine hydrochloride

Participants

Reaction Steps

In a round-bottomed flask, (S)-2-methyl-propane-2-sulfinic acid ((R)-1-furan-2-yl-ethyl)-amide (514 mg, 2.27 mmol) was dissolved in methanol 4 ml) and hydrogen chloride (4.0 M in 1,4-dioxane, 1.2 ml, 4.8 mmol) was added dropwise. The reaction mixture was stirred at room temperature for 15 min then concentrated to give 416 mg of (R)-1-furan-2-yl-ethylamine hydrochloride as a dark brown waxy solid which was used without further purification.

Provenance & Evidence