Trifluoroacetic acid → HCID 86677957, compound

Participants

Reaction Conditions

Reaction Steps

In a 100 mL round-bottomed flask, ((R)-3-cyano-1-methyl-propyl)-carbamic acid tert-butyl ester (158 mg, 0.80 mmol) was combined with TFA (2 ml) and dichloromethane (8 mL) to give a colorless solution. The reaction mixture was stirred at 25° C. for 15 h. The solvent was evaporated to provide 53 mg (68%) of (R)-4-aminopentanenitrile trifluoroacetate which was used in the next step without further purification.

Provenance & Evidence