Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(2-BOC-aminophenyl)boronic acid → N-(2,6-dichlorobenzoyl)-4-[2-(tert-butoxycarbonylamino)phenyl]-L-phenylalanine methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (2-BOC-aminophenyl)boronic acid | HCID 2773226 | — |
| 반응물 | N-(2,6-dichlorobenzoyl)-4-bromo-L-phenylalanine methyl ester | HCID 54284267 | — |
| 생성물 | N-(2,6-dichlorobenzoyl)-4-[2-(tert-butoxycarbonylamino)phenyl]-L-phenylalanine methyl ester | HCID 54237195 | 73.5% |
반응 단계
2-(tert-Butoxycarbonylamino)benzeneboronic acid (0.3 g) was coupled with N-(2,6-dichlorobenzoyl)-4-bromo-L-phenylalanine methyl ester (270 mg) by a similar procedure as described in Examples 15 to give 250 mg of N-(2,6-dichlorobenzoyl)-4-[2-(tert-butoxycarbonylamino)phenyl]-L-phenylalanine methyl ester. ESMS: m/z 543 (MH+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06855843B2 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-9e9e7ed7d7784aeeb6a0a3f6851d529b |
| 출처 메모 | uspto-grants-2005_02 |