Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 24636Generated: October 25, 2026

Trifluoroacetic acid → N-(2,6-dichlorobenzoyl)-4-(2-aminophenyl)-L-phenylalanine methyl ester TFA salt

https://huagongshe.com/reaction/24636

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantN-(2,6-dichlorobenzoyl)-4-[2-(tert-butoxycarbonylamino)phenyl]-L-phenylalanine methyl esterHCID 54237195—
ProductN-(2,6-dichlorobenzoyl)-4-(2-aminophenyl)-L-phenylalanine methyl ester TFA saltHCID 131723775—

Reaction Steps

N-(2,6-Dichlorobenzoyl)-4-[2-(tert-butoxycarbonylamino)phenyl]-L-phenylalanine methyl ester (90 mg) was treated with TFA (1 mL) for 2 h at room temperature. Excess TFA was removed in vacuo to give N-(2,6-dichlorobenzoyl)-4-(2-aminophenyl)-L-phenylalanine methyl ester TFA salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06855843B2
Source datasetuspto-grants-2005_02
ORD IDord-b731f018ac164ec5af167865138d4778
Source noteuspto-grants-2005_02