反应详情

A solution of 2benzyl-3-chloro-5-methoxy-2H-1,2,4,6-thiatriazine-1,1-dioxide (3.8 g) in methylene chloride (10 ml) is added dropwise to a stirred mixture of p-nitrophenol (1.7 g) and pyridine (2.4 g) in methylene chloride (20 ml). The reaction mixture is heated to reflux for 3 hours, cooled, washed with 3N aq. HCl and sat'd aq. Na2CO3. The methylene chloride layer is dried, filtered and evaporated in vacuo yielding the desired product as an oil.

1. temperatureThe reaction mixture is heated
2. temperatureto reflux for 3 hours
3. temperaturecooled
4. washwashed with 3N aq. HCl
5. dry with materialThe methylene chloride layer is dried
6. filtrationfiltered
7. customevaporated in vacuo