反应详情

A solution of 3.93 gm of m-AMSA and 2.12 gm of D-galacturonic acid monohydrate in 325 ml of specially denatured 3A anhydrous ethanol at 70°-80° C. is filtered with suction. The filtrate is stirred and chilled to 0°-5° C., then stored at -20° C. for about 16 hours. The product is collected, washed with cold (about -20° C.) specially denatured 3A anhydrous ethanol, then with anhydrous diethyl ether and dried under reduced pressure at 50°-55° C. to give 3.9 gm of m-AMSA D-galacturonate. The salt obtained by this process retains a small amount about 3% of ethanol.

1. customat 70°-80° C.
2. filtrationis filtered with suction
3. temperaturechilled to 0°-5° C.
4. customThe product is collected
5. washwashed with cold (about -20° C.)
6. dry with materialwith anhydrous diethyl ether and dried under reduced pressure at 50°-55° C.